Pharmacology MCQ-3 For NIPER Exam-2017

1	MECHANISM OF ACTION OF DACTINOMYCIN IS A.INHIBIT TOPOISOMERASE –II B.CROSS LINKS DNA C.INHIBITS FUNCTIONS OF MICROTUBULES D.INHIBITS DNA POLYMERASE
2	DRUG WHEN COADMINISTERED WITH TERFENADINE MAY LEAD TO LIFE THREATENING CARDIAC DYSARRYTHMIA A.LOMAFLOXACINE    B.CLOFAZIMINE    C.ITRACONAZOLE     D.NEOMYCIN
3	ADVERSE EFFECT OF ONE OF THE DRUG INCLUDE AMENORRHEA, BONE MARROW DEPRESSION, GIT DISTRESS AND HAEMORRHAGIC DISTRESS. IDENTIFY A.CYCLIZINE    B. PIROXICAM    C.CYCLOPHOSHAMIDE     D.CIMETIDINE
4	VARICELLA ZOSTER IS CAUSATIVE  ORGANISM FOR       A.      SMALL POX          B. DERMATOPHYTOSIS          C.HERPES            D.INFETIOUS MONOMUCLEOSIS
5	ONE OF THE FOLLOWING IS CONFIRMED BY DNA DIAGNOSIS TEST       A.      HYPERURICEMIA           B. CYSTIC FIBROSIS         C.ACUTE PANCREATITIS          D.HYPERLIPIDEMIA
6	SULFASALAZINE IS A PRODRUG THAT IS ACTIVATED IN THE INTESTINE BY BACTERIAL ENZYMES A.AZOREDUCTASE    B.CHOLINE ESTERASE    C.GLUCURONYL TRANSFERASE    D.AMYLASE
7	MACROLIDE ANTIBIOTIC EXERTS THEIR ACTION BY      A.      INHIBITING TRANSCRIPTION      B.       ALTERING THE GENETIC CODE      C.      TERMINATING PROTEIN SYNTHESIS PREMATURELY      D.      POST TRANSLATION MODIFICATION
8	SELECTIVE BETA 2 STIMULANT A.CAFFEINE    B.SALBUTAMOL     C.PROPRANOLOL     D. BETAHISTINE
9	METOPROLOL IS SOMETIMES PREFERRED TO PROPRANOLOL BECAUSE       A.      IT HAS BOTH  ALPHA AND BETA ADRENERGIC BLOCKADE       B.      IT HAS BOTH VASODILATOR PROPERTIES AND BETA ADRENERGIC BLOCKADE      C.      IT IS A BETA ONE SELECTIVE ANTAGONIST AND IT DOES NOT ENTER THE BRAIN      D.      IT IS A BETA 2 SELECTIVE ANTAGONIST
10	ULTRA SHORT ACTING BARBITURATES HAVE BRIEF DURATION OF ACTION DUE TO A.HIGH DEGREE OF BINDING TO PLASMA PROTEINS B.LOW LIPID SOLUBILITY RESULTING IN A MINIMAL CONCENTRATION IN BRAIN C. METABOLISM IS SLOW IN LIVER D. RAPID RATE OF REIDTRIBUTION FROM THE BRAIN DUE TO ITS HIGH LIPOSOLUBILITY
	Answers: 1.a     2.c     3.c      4.a      5.b     6.a       7.d     8.b     9.c     10.d