Autocoid MCQS-1

1.      All are an antihistamines with piperazine rings except

A) terfinadine                 
b) cetrizine                
c) cinnarizine               
d) hydroxizine

2.      Terfinadine is a prodrug. Its active metabolite is

A) fexofinadine        
b) astemizole                    
c) malfinadine            
d) methfinadine

3.      Match the following

1. Guanylhistamine        a strongest H2 antagonist, orally given
2. Burimamide                b. Strong H2 antagonist orally given
3. Metiamide                   c. Weak H2 antagonist not orally
4. Cimetidine                  d. Partial H2 agonist

      A) 1-d, 2-c, 3-b, 4-a                                                         
      b) 1-d, 2-a, 3-b, 4-c

C) 1-d, 2-b, 3-c, 4-a                                                         
d) 1-a, 2-b, 3-c, 4-d

4.      Khellin is a bronchodilator from Ammi visnaga. Chemically it is

A) coumarin glycoside          
b) diterpenoid            
c) alkaloid          
d) anthraquinone

5.      Benorylate is a prodrug of

A) paracetamol & aspirin    
b) aspirin & sulindac 
c) nemiuslide  
d) aspirin & nemiuslide

6.      Match the following

1. Tetracycline            a. Zollinger Elison’s syndrom
2. Aspirin                    b. Crohn’s disease
3. Sulfasalazine           c. Reye’s syndrome
4. Omeperazole           d. Fanconi’s syndrome

      A) 1-d, 2-c, 3-b, 4-a                                                         
      b) 1-d, 2-a, 3-b, 4-c

C) 1-d, 2-b, 3-c, 4-a                                                         
d) 1-a, 2-b, 3-c, 4-d

7.      An active metabolite of Sulindac is

A) methyl sulphide                                        
b) methyl sulphur monooxide

c) methylsulphur dioxide                               
d) methyl SO4

8.      Match the following

1. Probenicid              a. Causes agranulocytosis
2. Colchicines             b. Uricosuric agent                                    
3. Sulfinpyrazole         c. Anti mitotic & anti gout
4. Phenylbutazone       d. Uricosuric agent decreases penicillin excretion

      A) 1-d, 2-c, 3-b, 4-a                                                        
       b) 1-d, 2-a, 3-b, 4-c

c) 1-d, 2-b, 3-c, 4-a                                                         
d) 1-a, 2-b, 3-c, 4-d

9.      An anti gout drug working as an antidote in copper poisoning ( Wilson’s disease) is

A) D-penicillamine          
b) colchicine             
c) probenicid               
d) allopurinol

10.  Match the following

1. Xanthine oxidase inhibitor           a. Oximes
2. Carbonic anhydrase inhibitor       b. Phosphoric acid
3. Cholinesterase inhibitor               c. Dichlorphenamide                                    
4. Cholinesterase activator               d. Allopurinol

      A) 1-d, 2-c, 3-b, 4-a                                                        
      b) 1-d, 2-a, 3-b, 4-c

C) 1-d, 2-b, 3-a, 4-c                                                         
d) 1-a, 2-b, 3-c, 4-d

1.A      2.A      3.A     4.A     5.A      6.A      7.A      8.A     9.A     10.A