1. Methadone is
A)
μ agonist b) k agonist c) k antagonist d) μ antagonist
2. All blocks sodium channel except
a)
Phenytoin b) carbamazepine c) ethosuccimide d) valproic acid
3. A vitamin that increases peripheral metabolism of
levodopa is
A)
biotin b) pyridoxine c) riboflavin d) vitamin k
4. GABA agonist acts by increasing
A)
hyperpolarisation b)
depolarization c) hypopolarisation d) repolarisation
5. Hyperpolarisation is
A)
chloride inc, pot dec b) chloride dec,
pot inc c) both increased d) both decreased
6. in parkinsonism , there is degeneration of neurons in
substantia nigra and nigrostriatal tract. This result in deficiency of dopamine
in
a. striatum
b.subthalamic neuron C.Lumbar
vein D.All
7..which
excitatory neurotransmitter producing pain in spinal cord
a.NMDA b.glutamate c.substance p d. glycine
8. which drug
does not show albumin protein binding
a.barbiturates b.lignocaine c.nsaids d.tolbutamide
9.used in
treatment of parkinsonism
a.l-dopa b.selegeline c.amantadine d.all
10.which of
the following drug is commonly used in prophylaxis of migraine
a.ergotamine b.methysergide c.sumatriptan d.propranolo
11..which is
not a positive symptom associated with schizophernia
a.hallucination b.anhedonia c.delusion d. disorganised thoughts
12.. which is
used in methanol poisoning
a.
disulfiram b.barbiturate c.benzodiazepine d.fomepizole
13. rabbit
syndrome is adverse effect of
a.typical
antipsychotic drugs, antiparkinsonian agents
b.atypical
antipsychotic drugs, antiparkinsonian agents
c.typical
antipsychotics only
d atypical
antipsychotics only
14. extrapyramidal side effect is major
adverse effect of
a.atypical
antipsychotics b.typical antipsychotics c.both
d.none
15..weight
gain is caused by which antipsychotic
category drugs
a.atypical
antipsychotic b.typical antip c.both d.none
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ANSWERS:1. A 2.C
3.B 4.A 5.A
6.A 7.D 8.B
9.D 10.D
11.B
12.D 13.C 14.B 15.A
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