Autocoid MCQS-3

1.      Match the following

1. Epoprostinol                    a. Reduces post partum hemorrhage
2. Misoprostol                      b. Peptic ulcer treatment
3. Dinoprostone                    c. Induces abortions
4. Carboprost                        d. Inhibits platlets aggregation

 a) 1-d, 2-c, 3-a, 4-b          
 b) 1-c, 2-d, 3-a, 4-b
C) 1-d, 2-b, 3-c, 4-a        
 d) 1-a, 2-b, 3-c, 4-d

2.      Asthma is induced by

A) histamine    
b) thromboxanes
c) lecuoterines      
d) all

3.      Match the following

1. Acetyl coA               a. Thromboxanes
2. Tryptophan               b. 2- ethyl amine imidazole
3. Histidine                   c. Serotonin
4. Arachadonic acid     d. Cholesterol

      a) 1-d, 2-c, 3-b, 4-a                                                               
      b) 1-a, 2-c, 3-b, 4-d

C) 1-d, 2-b, 3-c, 4-a                                          
 d) 1-a, 2-b, 3-c, 4-d

4.      A drug useful in Migraine is

A) risatriptan               
b) clonidine                   
c) clozapine          
d) both a & c

5.      Match the following

1. Progabide                  a. Neurokinin antagonist
2. Pergolide                   b. Gastrin antagonist
3. Proglumide               c. Dopamine agonist
4. Vofopitant                d. GABA agonist

      a) 1-d, 2-c, 3-b, 4-a            
      b) 1-a, 2-c, 3-b, 4-d

C) 1-d, 2-b, 3-c, 4-a          
d) 1-a, 2-b, 3-c, 4-d

6.      All are the side effects of H2 blockers & omeperazole except

 A) kidney stone      
 b) gynacomastia          
 c) hypergastrinemia     
 d) inhibits P450

7.      Match the following

1. Carbenoxlone                       a. Meperidine derivative
2. Mebeverine                           b. Increases prolactin release
3. Metaclopramide                    c. Smooth muscle relaxant(rauwolfia)
4. Loperamide                           d. Anti ulcer from liquorice

      a) 1-d, 2-c, 3-b, 4-a                                                 
      b) 1-a, 2-c, 3-b, 4-d

C) 1-d, 2-b, 3-c, 4-a                              
d) 1-a, 2-b, 3-c, 4-d

8.      Match the following

1. Anthraquinones/senna         a. Stimulant purgative
2. PEG                                     b. Osmotic purgative
3. Liquid paraffin                    c. Faecal softner
4. Methyl cellulose                 d. Bulk laxative

      a) 1-d, 2-c, 3-b, 4-a                                                       
      b) 1-a, 2-c, 3-b, 4-d

C) 1-d, 2-b, 3-c, 4-a                                                       
d) 1-a, 2-b, 3-c, 4-d

9.      Match the following

1. Rochelle’s salt                   a. Sodium potassium tartarate
2. Tegaresod                          b. Sulfasalazine
3. Crohn’s disease                 c. Partial serotonin agonist
4. Traveller’s diarrohea         d. Ciprofloxacin & doxycycline
5. Histamine & gastrin          e. Local hormone

      a) 1-a, 2-b, 3-d, 4-c, 5-e                                                         
      b) 1-a, 2-c, 3-b, 4-d, 5-e

C) 1-a, 2-d, 3-c, 4-b, 5-e                                                        
d) 1-a, 2-b, 3-c, 4-d, 5-e

10.  One is not a Mast cell stabilizer, identify

A) kitotifen    
b) pizotifen  
c) disodium chromoglycate    
 d) nedocromil 
 e) pemirolast

1.C      2.D     3.A     4.A    5.A      6.A      7.A      8.D     9.B     10.A