AUTONOMIC NERVOUS SYSTEM MCQS- 4

1.	in alzheimer disease i.cholinergic agonist like arecoline,bethanicol,oxotremorine have no effect on alzheimer disese treatment ii cholinergic agonist like arecoline,bethanicol,oxotremorine have effect on alzheimer disease but more peripheral adverse effect iii.anti cholinesterase like physostigmine have no effect on alzheimer disease iv. cholinesterase like physostigmine have  effect on alzheimer disease but more peripheral adverse effect select true a.ii,iv           b.i,ii,iii                 c.i,ii                         d.ii,iii	a
2.	which of the following anticholinestrase  was ist time used in alzheimer disease a.rivastigmine              b.tacrine             c.physostigmine       d.neostigmine	b
3.	which cholinesterase reactivators are used to restore neuromuscular transmission(other than atropine sulphate) a.oximes are used in organophosphate anti che poisioning b.pralidoxime c.pralidoxime is ineffective as an antidote to anti che like physostigmine,neostigmine d.all of these	d
4.	select the synthetic anticholinergic a.homatropine      b.ipratropium bromide               c.cyclopentolate d.all of these	c
5.	which of the following is a prodrug of adrenaline used topically in glaucoma: a. brimonidine             b. dipivefrine           c. phenylpropanolamine d. dorzolamide	b
6.	atropine does not antagonise the following feature of anticholinesterase poisoning: a. hypotension        b. central excitation             c. muscle paralysis d. bronchoconstriction	c
7.	the organ most sensitive to actions of atropine is: a. gastric glands     b. salivary gland    c. urinary bladder muscle    d. heart	b
8.	which of the following mydriatics has the fastest and briefest action: a. atropine     b. homatropine       c. tropicamide     d. cyclopentolate	c
9.	the following mydriatic does not produce cycloplegia: a. phenylephrine    b. tropicamide     c. cyclopentolate       d. homatropine	a
10.	which of the following is a noncatecholamine sympathomimetic: a. adrenaline     b. ephedrine        c. dopamine           d. isoprenaline	b
11.	choose the correct statement about nicotine: a. it selectively stimulates parasympathetic ganglia b. it has no clinical application c. it is used as an aid during smoking cessation d. it is used in alzheimer's disease	c
12.	which of the following is false  about atropine a.mild anaesthetic action on cornea b.used as a anti motion sickness c.atropine is short acting as compare to hyoscine d. reflex due to light is absent in atropine treated rabbit	c
13.	which of the following is not a ganglion blocking agent a.ach             b.hexamethonium         c.pentolinium        d.anticholinestrase	a
14.	the rate limiting enzyme in the synthesis of catecholamines is: a. tyrosine hydroxylase                       b. dopa decarboxylase c. dopamine a-hydroxylase                 d. noradrenaline n-methyl transferase	a
15.	the most efficacious inhibitor of catecholamine synthesis in the body is: a. a-methyl-p-tyrosine              b. a-methyldopa c. a-methyl-norepinephrine      d. entacapone	a
16.	which of the following act as  a precursor  for dopamine,adrenaline,nor adrenaline a.phenylalanine          b.glycine         c.tryptophan           d.nicotine	a
17.	the following type/types of noradrenaline uptake is blocked by reserpine: a. axonal uptake     b. granular uptake         c. extraneuronal uptake d. all of the above	b
18.	the following is a selective a2 adrenoceptor antagonist: a. prazosin       b. phentolamine           c. yohimbine             d. clonidine	c
19.	the following sympathomimetic amine has agonistic action on a1 + a2 + b1 + b3 adrenoceptors, but not on b2 receptors: a. adrenaline       b. noradrenaline        c. isoprenaline          d. phenylephrine	b
20.	which of the following has no action on alpha receptor a.adrenaline         b.nor adrenaline           c.isoprenaline      d.both b and c	c