DRUGS IMPORTANT SIDE EFFECTS

DRUGS & THEIR SIDE EFFECTS
Nsaids	Peptic ulcer & vasocostriction
Chloramphenicol	Grey baby syndrome, bone marrow depression
Thizides diuretics	Hypokalemia, inhibits insulin secretion
Loop diuretics	Hypokalemia or low potassium ions concentration
Amiloride/triametrene	Heperkalemia or high potassium ions concentration
Isoniazid	Hepatotoxicity & neuropathy
Phenothiaznes	Goes in to retina (retinopathy)
Chlorpromazine	Goes in to retina (retinopathy)
Quinines	Goes in to retina (retinopathy)
Phenytoin	Acute hydantoin syndrome, cleft palate, hypoplastic nails
Sulfonamides	Anemia, cystalourea, kernicactus, steven johnson syndrome
Amino glycosides	Ototoxicity, nephrotoxicity, NM blocker, deafness
Floroquinones	Inhibits microsomal P450
Omeprazole	Inhibits microsomal P450
Dalaverdine	Inhibits microsomal P450
Rifampicin	Activates microsomal P450
Cigreete	Activates microsomal P450
Phenytoin	Activates microsomal P450
Alcohol	Activates microsomal P450
Barbiturates	Activates microsomal P450
Gresiofulvin	Activates microsomal P450
Zidovudine	Activates microsomal P450
Stavudine	Activates microsomal P450
Corticosteroids	Supression of adrenal hormones
Steroids	Peptic ulcer, euphoria, arthritis, cataract, cushing syndrome
Probenicid	Increases uric acids excretion, decreases penicilin excretion
Ephederine	Tachyphylaxis or destruction of NA store
Dopamine	Inhibits prolactin release
Metoclopramide	Increases prolactin (milk secretory hormone)
Domperidone	Increases prolactin (milk secretory hormone)
Fibrates	Increases insulin and kidney stone formation
Eno	Kidney stone formation after a long use
ACE inhibitors	Inhibits bradykinin matabolism thus results cough
Diazoxide	Decreases insulin secretion
α2 agonists	Decreases insulin secretion
Thizides diuretics	Decreases insulin secretion
Fibrates	Increases insulin secretion
Heparin	Haematoma, thrombocytopenia (platelets defeciency)
Tetracycline	Complex formation with Ca in teeth, bone weakness,
	Fanconi syndrome or renal toxicity
Pyridoxine	Increases levo dopa's metabolism
Isoniazid	Increases pyridoxine excretion
Valproic acid	Inhibits barbiturates metabolism
Minoxidil	Hypertrichosis (hairs on palms)
Chloramphenicol	Hypothermia, grey baby syndrome, bone marrow depression
Paracatamol	Hepatotoxicity
Morphine	Constipation, pin point pupil, depression of lungs
Alcohol	Mental disturbances and inhibits physical growth
Testosterone	Musculinization of foetus
Bradykinin	Cough
Substance p	Cough and pain
Tetracycline	Fanconi syndrome or renal toxicity
Rifampicin	Flu like syndrome or fever
Pyrazinamide	Hyperuricemia
Oral hypoglycemics	Hyporglycemia
Aspirin	Reye syndrome