Autocoid MCQS-6

1. Identify the drug choice for acute gout attack?

A.  Allopurinol      

b.Probenecid    

c. Colchicine    

d. Diclofenac & Colchicine

 2. All of the following are the roles of histamine except?

A. It increases appetite          

b.It produces sensation of itch

C.causes bronchoconstriction    

d.Increases gastric acid secretion

 3. Antihistaminic used to increase appetite in underweight children is

A. Cetrizine    

b.Loratidine      

c.Loxatidine    

d. Buclizine

4. Cetrizine is a active metabolite of

A.Hydroxyzine       

b.Promethazine      

c.Cimetidine      

d. Cinnarizine

5. Eicosanoids includes

A. Prostaglandins      

b. Leukotrienes      

c. Thromboxane   

d.All

6. In LTB₄ the subscript ‘4’ indicates

A.No. of double bonds       

b.No. of conjugated doubles bond

c.No. of  alkyl substitutions      

d. No. of halogens

7. Platelets primarily synthesize

A.TXA₂          

b. PGI₂            

c. LTB₄        

_D. Histamine

 8. Endothelium mainly generates

A.PGG₂       

_{B .}PGI₂      

_C. PAF     

D.PGF_2α

 9. All NASIDS are reversible inhibitors of cyclo oxygenase except

A.Aspirin       

b.Indomethacin      

c. Celecoxib      

d. Paracetamol

 10. N-acetyl-P-benzoquinoneimine is highly reactive heapatotoxic metabolite is of

A.Aspirin     

b.Indomethacin    

c. Paracetamol      

d.Ibuprofen

1.C   2.A       3.D      4.A      5.D       6.B       7.A      8.B      9.A     10.C