1. Nitric oxide releasing compounds are successful in
combination with
A) diuretics
b) NSAID’s
c) H1 blockers
d) H2 blockers
2. Basic ring present in Amiloride is
A) pteridine
b) pyrimidine
c) purine
d) pyrazine
3 an anti kaliuretic agent is
A) ethacrynic acid
b) spiranolactone
c) triamterene
d) furosemide
e) both b & c
4. Histamine is mainly involved in which
type of allergic reactions?
a. A. Type 1
b. Type 2
c. Type 3
d. Type 4
5. Which of the following is
antihistaminic, anticholinergic and 5HT antagonist?
A.Cinnarizine
b. Cyprohetadine
c.
Mepyramine
d.Both a & b
6. N-acetylcysteine is used in the
poisoning of which NASID?
A. Aspirin
b.Indomethcin
c. Paracetamol
d. Sulindac
7.
Paracetamol is detoxified by
A.Glucuronide conjugation
b. Glutathione conjugation
c.Glycine conjugation
d.Sulphate conjugation
8.
Which of the following is prodrug & converted to sulfide active
metabolite?
A.Phenacetin
b. Sulindac
c.
Indomethacin
d. Nabumetone
9.
Lefluomide an anti rheumatoid drug inhibits
A.Thymidylate synthtase
b.Aldehyde dehydrogenase
c.Nuclear receptor
activation
d. Dihydro-orotate
dehydrogenase
10. Identify the false statement about
Allopurinol
A.Allopurinol is an analogue of hypoxanthine
B.Allopurinol is converted to alloxanthine by xanthine
oxidase
C.Allopurinol increases uric acid excretion
D.Used as prophylactic as the drug of choice in the
long-term treatment of gout, but it is ineffective in the treatment of an acute
attack and may even exacerbate the inflammation.
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1.B 2.D
3.E 4.A 5.A
6.C 7.B 8.B 9.A 10.C
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