Saturday 25 February 2017

Pharmacology MCQS-1 For NIPER Exam 2017

1
   
Which of the antineoplastic agent is metabolised by xanthine oxidase
      a.       6-mercaptopurine     
      b.vincristine     
      c.chlorambucil         
      d. 6-thioguanine 

2

Polyenes antibiotics such as amphotericib –b  are most likely to
      a.       inhibit bacterial dna synthesis    
      b. bind to prokaryotic ribosomes
      c.act as antimetabolite    
      d. react with sterols in the membrane
3
  
Among the following statement one of them is most appropriate for  γ-interferon identify
     a.       they are virus specific substance amd not host specific, naturally occurring glycoproteins.
     b.      they are not virus specific substance however they are naturally occurring glycoproteins
     c.       they are not virus specific substances however they are not specific either. they are naturally occurring glycoproteins.
     d.      they are virus specific and host specific naturally occurring glycoproteins

4
  
A list of ACE INHIBITORS IS GIVEN BELOW. ONE OF THEM IS NOT PRODRUG. IDENTIFY
     A .      BENZEPRIL    
     B. CAPTOPRIL       
     C.QUINAPRIL      
     D.RAMIPRIL
5

WHICH ONE OF THE FOLLOWING IS NOT A PHARMACOLOGICAL EFFECT OF MORPHINE
      A.      COSTRICTION OF PUPIL   
      B.CNS DEPRESSION   
      C.DIARRHOEA    
      D.RESPIRATORY
6

AMONG THE FOUR OPIOIDS GIVEN BELOW ONE OF THEM IS EQUIPOTENT ON µ, DELTA, K1, AND K3 RECEPTORS TYPE
A.FENTANYL   
B. METHADONE    
C.MORPHINE   
D.ETORPHINE
7

IDENTIFY ONE OF THE CARBONIC ANHYDRASE INHIBITOR THAT INHIBIT ONLY LUMINAL CARBONIC ANHYDRASE ENZYME
     A.      METHAZOLAMIDE   
     B. ACETAZOLAMIDE   
     C. DICHLORPHENAMIDE   
      D.BENZOLAMIDE
8
WHICH ONE OF THE DRUG IS ALKYLATING AGENT
      A.      RIFAMPICIN   
      B.METHTREXATE   
      C.ALLOPURINOL   
      D.CYCLOPHOSPHAMIDE
9

AMONG THE IMMUNIZING AGENTS ONE OF THEM IS ORALLY ADMINISTERED
      A.      TETANUS TOXOID  
      B.RABIES VACCINE   
      C.POLIOMYELITIS VACCINE   
      D.MUMPS VIRUS VACCINE
10
   
ONE OF THE FOLLOWING STATEMENTS FOR ADENYL CYCLASEIS WRONG
       A.      IS A MEMBRANE BOUND ENZYME   
       B. INACTIVATED BY PHOSPHODIESTERASE
C.CATALYSES THE AMP FORMATION    
D.ACTIVE ONLY WHEN ASSOCIATED WITH G-PROTEIN

Answers:   1.c     2.d      3.a       4.c      5.c      6.d       7.d     8.d     9.c     10.d

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