Saturday 4 February 2017

CNS MCQ

1
The drug of choice in benzodiazopene poisoning is
A) picrotoxin                 b) flumazenil              c) naloxone                  d) gabapentin


2
Identify the drug blocking GABA receptor
A) gabapentin                b) picrotoxin               c) flumazenil               d) both b & c


3
Disulfiram is the drug used to stop alcohol habit. It act by inhibiting
A) alcohol dehydrogenase  b) aldehyde dehydrogense   c) both      d) acid dehydrogenase


4
An only local anesthetic causing vasoconstriction is
A) procaine                      b) benzocaine                   c) bupivacaine                d) cocaine

5
Match the following
  1. Mania (bipolar)                                                          a Lithium
  2. Bed wetting treatment                                                b. Disulfiram & propanolol
  3. Alcohol withdrawl                                                      c. Imipramine
Lithium ions
a) 1-c, 2-a, 3-b                                                         b) 1-a, 2-b, 3-c
C) 1-a, 2-c, 3-b                                                        d) 1-c, 2-b, 3-a

6
GABA agonist acts by increasing
A) hyperpolarisation      b) depolarization  c) hypopolarisation          d) repolarisation


7
Hyperpolarisation is
A) chloride inc, pot dec  b) chloride dec, pot inc    c) both increased  d) both decreased

8
which excitatory neurotransmitter producing pain in spinal cord
a.NMDA       b.glutamate         c.substance p          d. glycine

9
which drug does not show albumin protein binding
a.barbiturates      b.lignocaine         c.nsaids           d.tolbutamide

10
which is not a positive symptom associated with schizophernia
a.hallucination     b.anhedonia       c.delusion      d. disorganised thoughts

11
which is used in methanol poisoning
a. disulfiram      b.barbiturate       c.benzodiazepine       d.fomepizole
12
 rabbit syndrome is adverse effect of
a.typical antipsychotic drugs, antiparkinsonian agents
b.atypical antipsychotic drugs, antiparkinsonian agents
c.typical antipsychotics only
d atypical antipsychotics only

13
extrapyramidal side effect is  major adverse effect of
a.atypical antipsychotics    b.typical antipsychotics    c.both     d.none

14
weight gain is caused by which antipsychotic  category drugs
a.atypical antipsychotic    b.typical antip     c.both        d.none

15
amenorrhoea ,galactorrhoea and gynaecomastia are adverse effect of
a.atypical antipsychotics    b.typical antipsychotics    c.both    d.parkinsonian agents

16
drug used in mania
a.lithium    b.valproate     c.atypical antipsychoyics       d all

17
cannabinoids are used as hallucinogens and tetrahydrocannabinol is active constituent of ‘cannabis indica’. now match the source of following
a bhang       1. dried female inflorescence
b.ganja         2 dried leaves
c.charas       3.dried resinous extract from flowering tops and leaves
select correct
A.      a-1,b-2,c-3
B.      a-2,b-1,c-3
C.      a-1,b-3,c-2
D.      a-2,b-3,c-1

18
which of the following is ultra short acting barbiturate
a.methohexitone     b.thiopentone      c.pentobarbitone        d. a and b

19
dopaminergic overactivity in limbic system is related with
a.parkinsonism    b.schozophernia    c.depression      c.all of these

20
methanol poisionig cause retinal damage(blindness)  which is caused by
a.methanol    b.formaldehyde      c.formic acid      d.all of these

21
which of the  following is not a atypical antipsychotics
a.risperidone     b.fluphenazine     c.olanzapine       d.aripiprazole


Answer:     1. B          2. D            3. B          4. D          5. C               6. A          7.A             8. D         9. B            10. B        11. D        12. C              13. B            14.A  15. B          16. D        17. B          18. D        19. B        20. C              21. B


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