CNS MCQS-3

1	Morphine sulphate is A.acidic      b. Alkaline              c.neutral          d.all	B
2	Which of the follwing is not the use of morphine A.analgesic     b.cough      c.diarrhoea      d.antacid	D
3	Match the following A.naloxone                                              1.pure antagonist B.nalorphine                                           2.agonist/antagonist C.buprenorphine                                    3.partial mu agonist and kappa antagonist Correct match a.     A-1,b-2,c-3 b.     A-2,b-1,c-3 c.     A-3-b-1,c-2 d.     A-1,b-3,c-2	A
4	Which of the antichoinesterase drug used in alzheimers disease A.neostigmine    b.pyrodstigmine    c.rivastigmine    d.physostigmine	C
5	Pyritinol consists of two molecules of pyridoxine (vitamine B6). A.this pyritinol molecule has vitmine B6 activity B. This pyritinol molecule has no vitmine B6 acticity C. This pyritinol molecule cause dementia D this pyritinol molecule has antialzheimers activity Which statement is correct A.    B,c    b. A,c   c. A,d       d.b,d	D
6	Select true A.    Thiopental is ultra short acting barbiturate B.    Phenobarbital is long acting barbiturate C.    Triazolam is short acting benzodiazepine D.    All	d
7	Barbiturates a.     Have low therapeutic index b.     Affect REM sleep c.     It cause physical dependence and abuse d.     Induce the microsomal enzyme activity. Due to this metabolism of anticoaguants, digitalis and glucocorticoid increases. e.     All of these	E
8	Which hypnotic is also used for induction of anaesthesia A.    Triazolam     b. Thiopental      c. Phenobarbital    d. All	b
9	Overdose of hypnotics cause death- select usual cause of death A) depression of the medullary  respiratory center B) stroke         c. Brain haemorrhage                                      d) all	A
10	An antiepileptic drug act by  inhibiting central action of excitatory amino acids: a) ethosuximide     b) phenobarbitone       c) lamotrigine        d) all	c
11	Drug for generalized tonic-clonic and  partial and seizures is: a) phenytoin       b) valproate        c) carbamazepine      d) all of the above	D
12	Most effective drug for status epilepticus in  adult is a) diazepam      b) carbamazepine      c) lamotrigine       d) zonisamide	A
13	Phenytoin drug is used for a) myoclonic seizures     b) grand mal epilepsy    c) petit mal epilepsy d) all of the above	B
14	Most effective drug for status epilepticus in  infants and children: a) phenobarbital sodium      b) clonazepam    c) lamotrigene           d)all	A
15	Antiepileptic drug inhibitor of GABA aminotransferase (GABA-T) is: a) ethosuximide       b) Phenobarbital         c) vigabatrin        d) primidone	C
16	Name antiparkinsonian drug which is preferred for treatment of the drug-induced  parkinsonism: a)benserazide          b) ropinirole          c) benztropine         d) levodopa	C
17	Which vitamin reduces the effect of levodopa A.    Vitain B12       b.Vitamin C        c.Vitamin B6     d. All	C
18	Name the drug which antagonise the effect of levodopa A.haloperidol     b. Clozapine     c.chlorpromazine   d. All	D
19	Alcohol cause a.Increase body heat loss      b.Vasodilation c.Cns depression                  d.All	D
20	Name the opioid receptor which is  responsible for euphoria and respiratory depression A) mu-receptors      B) delta-receptors      C) kappa-receptors     D) all of the above	A
21	Mu (μ) receptors activation cause A) analgesia, respiratory depression, physical dependence, , euphoria B) analgesia, euphoria,  physical dependence, respiratory stimulation C)  hallucinations, respiratory and vasomotor stimulation D) mydriasis, physical dependence ,sedation, spinal analgesia	A
22	Name the opioid receptor  which is associated with  vasomotor stimulation and dysphoria A) mu-receptors      B) delta-receptors        C kappa-receptors      D) all of the above	C
23	Select  opioid analgesics which is natural and  strong mu receptor agonist A) morphine         B) naloxone          C) meperidine           D) buprenorphine	A
24	Morphine causes a.Urinary retention      b.Brinchial constriction     c.Constipation       d.All	D
25	high therapeutic index drug is a.lithium    b. barbiturates    c.theophylline      d.benzodiazepines	d
26	Select wrong pair a.     algesia------pain killer b.     anhedonia----loss of interest c.     obsessive compulsive disorder-----recurrent intrusive thoughts d.     mania----cyclic manic and depressive phase e.     euphoria-----feeling of intense pleasure	a
27	Select false a.wines are obtained from fruits fermentation like grape b.beers are obtained from fementation of cereals c.absolute alcohol is is also known as hydrated alcohol d.all	c
28	Which of the following alcoholic beverage is distilled product a.beer     b.wine     c.rum/whisky    d. none	c
29	Absolute alcohol is a.99% w/v ethanol    b.99% w/w ethanol  c.95% w/w ethanol    d.95% w/v ethanol	b
30	At high concentration Theophylline and Phenytoin  follows which order of elimination a.Ist order   b.zero order      c. second order   d. all	b
31	T1/2 of which drug is shorter in children than adults a.theophylline       b.phenytoin      c. carbamazepine     d. all	d
32	Name the drug which have different action through different routes a.phenytoin     b.carbamazepine   c. theophylline    d. all	a