Autocoid MCQS-2

1.      A diuretic that reduces insulin secretion is

A) indapamide            
b) furosemide           
c) acetazolamide        
d) amiloride

2.      Match the following

1. Glucocorticoids            a. Aldosterone receptor antagonist
2. Thiazides                      b. Metabolite of spiranolactone
3. Canrenone                    c. Structure same as diazoxide
4. Eplerenone                   d. Anti-inflammatory

      A) 1-d, 2-c, 3-b, 4-a                            
      b) 1-d, 2-a, 3-b, 4-c

C) 1-d, 2-b, 3-c, 4-a                                                         
d) 1-a, 2-d, 3-b, 4-c

3.      Anaphylaxis is caused by histamine & treated by adrenaline. It is

A) vasodilation & bronchoconstriction           
b) vasodilation & bronchodilation

C) vasoconstriction & bronchodilation          
d) vasoconstriction & bronchoconstricton

4.       Basic ring present in Histamine & tryptophan are

A) indole & pyrrole                               
 b) imidazole & quinoline

 c) imidazole & indole                            
d) indole & imidazole

5.      Match the following

1. Motion sickness             a. Aceatazolamide
2. Morning sickness           b. Dimenhydrinate
3. Sea/air sickness              c. Promethazine
4. Mountain sickness         d. Hyoscine

      a) 1-d, 2-c, 3-a, 4-b                                                        
      b) 1-c, 2-d, 3-a, 4-b

C) 1-d, 2-c, 3-b, 4-a                                               
d) 1-a, 2-b, 3-c, 4-d

6.      Two drugs blocks histamine, serotonin, cholinergic receptors. Identify

A) cinnarizine & promethazine                                      
b) cinnarizine & cyprohepatadine

C) promethazine & cyprohepatadine                             
d) terfenadine & cinnarizine

7.      One is not a serotonin agonist

A) cisapride            
b) sumatriptan                   
c) buspiron                 
d) clozapine

8.      Serotonin antagonist chiefly used in vomiting is

A) ondensteron        
b) ketanserin                    
c) methylsergide        
d) pizotifen

9.      One drug is not used in Raynaud’s disease

A) ginkgo                 
b) reserpine                       
c) ketanserin              
 d) risperidone

10.  One is not a selective COX2 inhibitor

A) diclofenac           
b) sulindac                         
c) celecoxib                
d) both a and b

1.A    2.A     3.A    4. C      5.C      6.B       7.D        8.A       9.D       10.D