CNS MCQS-1

1	The drug of choice in benzodiazopene poisoning is A) picrotoxin                 b) flumazenil              c) naloxone                  d) gabapentin	b
2	Identify the drug blocking GABA receptor A) gabapentin                b) picrotoxin               c) flumazenil               d) both b & c	d
3	Disulfiram is the drug used to stop alcohol habit. It act by inhibiting A) alcohol dehydrogenase  b) aldehyde dehydrogense   c) both      d) acid dehydrogenase	b
4	An only local anesthetic causing vasoconstriction is A) procaine                      b) benzocaine                   c) bupivacaine                d) cocaine	d
5	Match the following 1.     Mania (bipolar)                                          a Lithium 2.     Bed wetting treatment                               b. Disulfiram & propanolol 3.     Alcohol withdrawl                                      c. Imipramine a) 1-c, 2-a, 3-b                                                         b) 1-a, 2-b, 3-c c) 1-a, 2-c, 3-b                                                        d) 1-c, 2-b, 3-a	c
6	GABA agonist acts by increasing A) hyperpolarisation      b) depolarization  c) hypopolarisation          d) repolarisation	a
7	Hyperpolarisation is A) chloride inc, pot dec  b) chloride dec, pot inc    c) both increased  d) both decreased	a
8	which excitatory neurotransmitter producing pain in spinal cord a.NMDA       b.glutamate         c.substance p          d. glycine	b
9	which drug does not show albumin protein binding a.barbiturates      b.lignocaine         c.nsaids           d.tolbutamide	b
10	which is not a positive symptom associated with schizophernia a.hallucination     b.anhedonia       c.delusion      d. disorganised thoughts	b
11	which is used in methanol poisoning a. disulfiram      b.barbiturate       c.benzodiazepine       d.fomepizole	d
12	rabbit syndrome is adverse effect of a.typical antipsychotic drugs, antiparkinsonian agents b.atypical antipsychotic drugs, antiparkinsonian agents c.typical antipsychotics only d atypical antipsychotics only	c
13	extrapyramidal side effect is  major adverse effect of a.atypical antipsychotics    b.typical antipsychotics    c.both     d.none	b
14	weight gain is caused by which antipsychotic  category drugs a.atypical antipsychotic    b.typical antip     c.both        d.none	a
15	amenorrhoea ,galactorrhoea and gynaecomastia are adverse effect of a.atypical antipsychotics    b.typical antipsychotics    c.both    d.parkinsonian agents	b
16	drug used in mania a.lithium    b.valproate     c.atypical antipsychoyics       d all	d
17	cannabinoids are used as hallucinogens and tetrahydrocannabinol is active constituent of ‘cannabis indica’. now match the source of following a bhang       1. dried female inflorescence b.ganja         2 dried leaves c.charas       3.dried resinous extract from flowering tops and leaves select correct A.    a-1,b-2,c-3 B.    a-2,b-1,c-3 C.    a-1,b-3,c-2 D.    a-2,b-3,c-1	b
18	which of the following is ultra short acting barbiturate a.methohexitone     b.thiopentone      c.pentobarbitone        d. a and b	d
19	competitive antagonist at bzd site a.muscimol      b.bicuculline       c.flumazenil      d.beta carboline
20	dopaminergic overactivity in limbic system is related with a.parkinsonism    b.schozophernia    c.depression      c.all of these	b
21	methanol poisionig cause retinal damage(blindness)  which is caused by a.methanol    b.formaldehyde      c.formic acid      d.all of these	c
22	which of the  following is not a atypical antipsychotics a.risperidone     b.fluphenazine     c.olanzapine       d.aripiprazole	b