ANTI TUBERCULAR, ANTI LEPROTIC, ANTIFUNGAL ANTI VIRAL MCQS

1	methenamine on conversion in acidic ph release a.nitrous oxide    b. nitric oxide   c.nitrate       d.formaldehyde	d
2	pyridoxine is given with isoniazid to treat which side effect of isoniazid a.neurotoxicity      b.nephrotoxicity    c.both of these     d.hepatic toxicity	a
3	isoniazid is highly active in a.acidic medium  b.basic medium    c.both a and b     d.none of these	c
4	which of the following is a prodrug a.sulfasalazine      b.isoniazid      c.both a and b      d.none of these	c
5	major side effect of ist line antitubercular drugs is a.hepatitis    b.nephrotoxicity    c.neurotoxicity     d.ototoxicity	a
6	loss of visual acuity/colour blindness is side effect of which antitb a.isoniazid    b.rifampin       c.ethambutol     d.streptomycin	c
7	use of which antitb cause urine colour orange red a.rifampin      b.ethambutol    c.both of these    d.isoniazid	a
8	cycloserine is obtained from a.s.ritodrine       b.s.orchidaceus    c.s.rhizopus   d.s. chryosogenum	b
9	flu syndrome,cutaneous syndrome, respiratory syndrome caused by a.ethambutol    b.cycloserine    c.rifampin      d.pyrazinamide	c
10	rifampin act by inhibiting a.dna dependent rna polymerase      b.rna dependent dna polymerase c.cell wall synthesis                             d.protein synthesis	a
11	dots was recommended by who in a.1990    b.1995      c.1998      d.1999	b
12	which antitb is not safe during pregnancy a.isoniazid      b.rifampin    c.streptomycin      d.all of these	c
13	least toxic polyene is a.ampphotericin b    b.nystatin    c.hamycin     d.natamycin	a
14	which of the following antifungal is not used systemically a.fluconazole    b.itraconazole     c.ketoconazole    d.clotrimazole	d
15	which polyene antifungal developed by india a.amb    b.nystatin    c.hamycin     d.natamycin	c
16	which antifungal deposited in hair a.amb     b.flucytosine     c.griseofulvine     d.naftefine	c
17	cushing syndrome is caused by a.ketoconazole   b.itraconazole    c.both of these   d.none of these	d
18	which antifungal is not water soluble a.amb    b.flucytosine    c.ketoconazole    d.itraconazole	a
19	which antifungal is nephrotoxic a.amb   b.ketoconazole    c.itraconazole   d.both a and b	a
20	which antifungal is narrow spectrum a.amb   b.flucytosine    c.ketoconazole    d.clotrimazole	b
21	which of the following is least toxic antifungal a.amb    b.flucytosine   c.triazoles   d.imidazoles	c
22	which antiviral is effective against dna containing  virus a.zidovudine    b.ganciclovir      c.abacabir       d.lopinavir	b
23	select the protease inhibitor a.efavirenz     b.zalcitabine        c.didanosine     d.ritonavir	d
24	which of the following antiviral is thymidine analogue a.idoxuridine      b.acyclovir    c.famciclovir    d.valacyclovir	a
25	valaciclovir is a prodrug of a.aciclovir     b.famciclovir     c.ganciclovir       d.none of these	a
26	which anti herpes(anti viral) is most effective against cytomegalovirus a.acyclovir     b.valaciclovir     c.ganciclovir    d.all equally effective	c
27	select anti herpes which is not a analogue of nucleic acid a.foscarnate      b.abacavir     c.idoxuridine     d.all of these	a
28	nelfinavir belongs to the following category a.nrti    b.nnrti      c.protease inhibitors    d.none of these	c
29	which of the following is pyrimidine analogue a.idoxuridine     b.trifluridine    c.vidarabine     d.all of these	d
30	haart full form a.highly active antiretroviral therapy b.highly acquired antiretroviral therapy c.heavily attained antiretroviral therapy d.highly attained antiretroviral therapy	a
31	therapy with 3 antiretroviral drug is considered optimal.the 3 drug regimen should belong to(except advance cases) a.3 different classes    b.2 different classes     c.1 class        d.none of these	b
32	which antiviral drug used(safe) during pregnancy(to save the child from hiv) a.didanosine      b.zidovudine   c.idoxuridine    d.famciclovir	b
33	antiretroviral combination should be avoided a.zidovudine+stasudine         b.stavudine+didanosine c.lamivudine+didanosine       d.all of these	d
34	anti influnza drug a.amantadine    b.oseltamivir    c.both a and b   d.none	c