Pharmacology MCQS-2 For NIPER Exam 2017

1	ANTIARRYTHMIC THAT IS PRIMARILY INDICATED FOR TREATMENT OF SUPRA VENTRICULAR TACHYARRYTHMIAS A.MEXILETINE    B. DILITAZEM    C.NIFEDIPINE    D. PROPRANOLOL
2	ANTIVIRAL AGENTS EXHIBIT THE GREATEST SELECTIVE TOXICITY FOR THE INVADING VIRUS A.AMANTADINE    B.ZIDOVUDINE     C.IDOXURIDINE     D.ACYCLOVIR
3	THE DRUG THAT OFTEN CAUSES TACHYCARDIA WHEN GIVEN IN REGULAR DOSES A.VERAPAMIL   B.GUANNETHIDINE    C.PROPRANOLOL     D.ISOSORBIDE DINITRATE
4	PURPOSE OF A COMBINED DRUG REGIMEN IN TUBERCLOSIS IS TO      A.      TO DELAY THE EMERGENCE OF DRUG RESISTANCE      B.       REDUCE THE DURATION OF ACTIVE THERAPY      C.      SCHEDULE THE ONSET OF THERAPY      D.      PROMOTE A PLACEBO EFFECT ON THE PATIENT
5	SELECTIVE SEROTONIN REUPTAKE INHIBITOR A.DESIPRAMINE     B. FLUOXETINE     C.BUPROPIONE    D.MAPROTILINE
6	PLASMODIAL RESISTANCE OF CHLOROQUINE IS DUE TO      A.      INDUCTION OF INACTIVATING ENZYMES      B.       CHANGE IN RECEPTOR STRUCTURES      C.      C.INCREASED IN THE ACTIVITY OF DNA REPAIR MECHANISM      D.      DECREASED CARRIER MEDIATED DRUG TRANSPORT
7	ACTIONS OF OPOID ANALGESICS IS MEDIATED VIA KAPPA RECEPTORS      A.      CEREBRAL VASCULAR DILATION      B.      EUPHORIA         C.SPINAL ANALGESIA          D. PHYSICAL DEPENDENCE
8	ONE OF THE FOLLOWING DRUG HAS ACTIVITY AGAINST HERPES SIMPLEX VIRUS TYPE I AND IS USED TOPICALLY. SYSTEMIC ADMINISTRATION OF THE SAME RESULTS IN BONE MARROW DEPRESSION, HEPATIC DYSFUNCTION AND NEPHROTOXICITY A.ACYCLOVIR    B. AMANTADINE     C.VIDARABINE     d.IDOXURIDINE
9	DRUG COMBINATION WARFARIN/VITAMIN K RESULTS IN SPECIFIC INTERACTION A.ANTAGONISTIC      B.INCREASED SEDATION    C.NO INTERACTION    D. HARMFUL IN PRESENCE OF OXIDIZING AGENTS
10	MECHANISM OF DIGITALIS IS      A.      DECREASED INTRA CELLULAR Na CONCENTRATION      B.      INHIBITS Na-K ATPase      C.      ACTIVATED ADENYL CYCLASE WHICH PRODUCES c-AMP      D.      DECREASED RELEASE OF CALCIUM FROM SARCOPLASMIC RETICULUM
	Answers:1.b       2.d     3.b    4.b     5.b      6.d      7.c     8.d     9.a     10.b

Pharmacology MCQS-1 For NIPER Exam 2017

1	Which of the antineoplastic agent is metabolised by xanthine oxidase       a.       6-mercaptopurine            b.vincristine            c.chlorambucil                d. 6-thioguanine
2	Polyenes antibiotics such as amphotericib –b  are most likely to       a.       inhibit bacterial dna synthesis           b. bind to prokaryotic ribosomes       c.act as antimetabolite           d. react with sterols in the membrane
3	Among the following statement one of them is most appropriate for  γ-interferon identify      a.       they are virus specific substance amd not host specific, naturally occurring glycoproteins.      b.      they are not virus specific substance however they are naturally occurring glycoproteins      c.       they are not virus specific substances however they are not specific either. they are naturally occurring glycoproteins.      d.      they are virus specific and host specific naturally occurring glycoproteins
4	A list of ACE INHIBITORS IS GIVEN BELOW. ONE OF THEM IS NOT PRODRUG. IDENTIFY      A .      BENZEPRIL          B. CAPTOPRIL             C.QUINAPRIL            D.RAMIPRIL
5	WHICH ONE OF THE FOLLOWING IS NOT A PHARMACOLOGICAL EFFECT OF MORPHINE       A.      COSTRICTION OF PUPIL          B.CNS DEPRESSION          C.DIARRHOEA           D.RESPIRATORY
6	AMONG THE FOUR OPIOIDS GIVEN BELOW ONE OF THEM IS EQUIPOTENT ON µ, DELTA, K1, AND K3 RECEPTORS TYPE A.FENTANYL    B. METHADONE     C.MORPHINE    D.ETORPHINE
7	IDENTIFY ONE OF THE CARBONIC ANHYDRASE INHIBITOR THAT INHIBIT ONLY LUMINAL CARBONIC ANHYDRASE ENZYME      A.      METHAZOLAMIDE         B. ACETAZOLAMIDE         C. DICHLORPHENAMIDE          D.BENZOLAMIDE
8	WHICH ONE OF THE DRUG IS ALKYLATING AGENT       A.      RIFAMPICIN          B.METHTREXATE          C.ALLOPURINOL          D.CYCLOPHOSPHAMIDE
9	AMONG THE IMMUNIZING AGENTS ONE OF THEM IS ORALLY ADMINISTERED       A.      TETANUS TOXOID         B.RABIES VACCINE          C.POLIOMYELITIS VACCINE          D.MUMPS VIRUS VACCINE
10	ONE OF THE FOLLOWING STATEMENTS FOR ADENYL CYCLASEIS WRONG        A.      IS A MEMBRANE BOUND ENZYME           B. INACTIVATED BY PHOSPHODIESTERASE C.CATALYSES THE AMP FORMATION     D.ACTIVE ONLY WHEN ASSOCIATED WITH G-PROTEIN
	Answers:   1.c     2.d      3.a       4.c      5.c      6.d       7.d     8.d     9.c     10.d

Walk-in for Research Associate: Mankind

ORGANIC CHEMISTRY MCQS: PREVIOUS NIPER PAPER : 2008-2012

1.       ONE QUESTION ON WOODWARD FIESER REACTION- 2012

2.       0NE QUESTION ON ESTER FORMATION- 2012

3.       0NE QUESTION ON CANNIZARO REACTION-2012

4.       PRODUCT FORMATION AFTER REACTION OF BENZENE AND N-PROPYL CHLORIDE IN PRESENCE OF AlCl3-2012

5.       ALLENE HYBIRDISATION-2012

6.       NUCLEOPHILIC SUBSTITUTION TAKE PLACE THROUGH BENZYNE FORMATION, IN WHICH OF THE FOLLOWING: 2011 A.PICRIC ACID      B.NITRO BENZENE     C.PARA METHOXY NITRO BENZENE

7.       BOND STRENGTH ORDER: 2011 1.       C-H     2. C-C      3. H-H     4. C-CL

8.       SELECT MORE OF THE FOLLOWING:  1. PYRIDINE    2.ANILINE     3.PYRROLE     4. N,N DIMETHYL ANILINE: 2011

9.       ONE QUESTION ON SN2 REACTION: 2011

10.   CYCLOADDITION OCCUR BY……2011 ANSWER  DIELS ALDER REACTION

11.   NON MIRROR ISOMER IMAGES ARE CALLED: 2010

12.   WHICH IS THE OPTICAL ISOMER: 2010 A.      BIPHENYLS   B.ARENES    C. MESO TARTARIC ACID     D. NONE

13.   GEOMETRY OF CCL4 (SYMMETRY SHOWN BY CARBON TETRA CHLORIDE): 2010

14.   SELECT THE AMPHIPATHIC: 2010 A.NUCLEOTIDE B.FATTY ACID C.AMINO ACID

15.   CIS AND TRANS CITRIC ACID ARE:2010 DIASTERIOISOMER    OR ENANTIOMER

16.   0NE QUESTION ON: IDENTIFY  GIVEN CONFIGURATION IS R OR S:2010

17.   GIVE DIFFERENT CLASS OF GROP:2010 A.      SANDMAYER REACTION B.      VELSMEIR REACTION C.      GATTERMAN REACTION D.      RIMMER TIMAN REACTION

18.   SELECT THE HIGHLY ELECTRO DONATING GROUP:2010 A.CN    B. NH2

19.   ARRANGE ACCORDING TO BOND ENERGY:2010 A.      C-H B.      H-CL C.      C-CL D.      CL-CL

20.   C6H5COCH3 IS CONVERTED INTO C6H5CH2CH3 IN WHICH REACTION:2010

21.   ETHYLACETOACETATE IS THE PRODUCT OF WHICH REACTION:2010

22.   HOMO ANNULAR DIENE: SELECT WHICH OF THE FOLLOWING:2010

23.   3 QUESTION ON WOOD WARD FISCHER REACTION:2010

24.   IDENTIFY THE FIGURE(figure was given): 2010 A.      HALF CHAIR B.      TWISTED BOAT C.      BOAT

25.   ONE QUESTION ON SN2 REACTION: 2009

26.   2 QUESTION ON CIS AND TRANS CONFIGURATION: 2009

27.   2 QUESTION ON R AND S CONFIGURATION:2009

28.   DOUBLE BOND DETERMINED BY:2009 A.      OZONOLYSIS B.      BROMINATION C.      HYDROGENATION

29.   ANTIMARKONIKOV ADDITION OF HBr TO Styrene GIVES:2009 ANSWER:Ph-CH2-CH2-Br

30.   POLYESTER IS MADE OF:2009

31.   CIS AND TRANS CINNAMIC ACID ARE: ENANTIOMER OR DIASTEREOISOMER:2009

32.   FROM GIVEN STRUCTURE: SELECT THE TYPE OF CONFIGURATION:2009 ANSWER: SAWHORSE CONFIGURATION

33.   ACTIVE ION IN FREIDAL CRAFT REACTION IS: ANSWER: CATION:2009

34.   SELECT THE MOST POLAR: 2008 A.ACETONE    2.CHLOROFORM    3.WATER    4.BENZENE

35.   0NE QUESTION ON DEFINATION OF ENANTIOMER:2008

36.   0NE QUESTION ON DEFINATION OF DIASTERIOISOMER:2008

37.   0NE QUESTION ON DEFINATION OF ANOMERS:2008

38.   0NE QUESTION ON DEFINATION OF ATROPOISOMER:2008

39.   IN SN2 REACTION C=O GROUP AFFECTED BY: BY NUCLEOPHILES PRESENCE:2008

40.   GIVE THE RELATION BETWEEN TO GIVEN STRUCTURE:2008 A.      ANOMER     B.EPIMERS     C. ENANTIOMERS        DIASTERIOISOMER

41.   GIVEN CONFIGURATION IS OF TYPE:2008 ANSWER: SAWHORSE PROJECTION

42.   CYCLOADDITION IS SEEN IN WHICH REACTION:2008 A.ALDOL CONDENSATION B.DIEL ELDERS REACTION C.CANNIZZARO REACTION

43.   INTERMEDIATE FORMED IN WITTIG REACTION: 2008

Hormone-MCQS

1. Which of the following hormone is released from anterior pituitary gland           a.        Parathormone                b.    thyroid stimulating hormone           C.    vasopressin                        d.    somatostatin	B
2. Somatotatin is released from pancreas as well as from          a.   Hypothalamus                  b.  anterior pituitary gland              C. posterior pituitary gland               d. All	A
3. Which hormone help in adaptation to stress          a.        Adrenaline               b.     Glucocorticoid                 c.    both                d.     parathormone	C
4. Which of the following help in maintenance of calcium balance          a.        Vitamin-d                b.     parathormone                  c.    calcitonin                 d.    all	D
5. Which of the following hormone is also released from placenta A.estrogen      b.prolactin         c.chorionic gonadotrophin      d.all	D
6. Match following 1. Dwarfism        a. Growth hormone deficiency in childs 2. Acromegaly     b. Growth hormone overproduction in adults 3. Gignatism          c. Growth hormone overproduction in childs 4. Addisons disease  d. Hyposecretion of sex hormone Select        a.       1-b, 2-a,3-c,4-d                    b.    1-a,2-b,3-c,4-d   C.     1-a,2-b,3-d,4-c          d.     1-a,2-c,3-b,4-d	B
7. Match the following         1.        Cushing syndrome     a. Hypersecretion of corticosteroid hormone         2.        Cretinism        b. Hyposecretion of thyroid hormone in childs         3.        Myxoedema     c. Hyposecretion of thyroid hormone in adults         4.        Graves disease   d. Autimmune  disease, igg antibodies form against tsh receptor Select a.1-a,2-b,3-c,4-d        b.1-a,2-c,3-b,4-d C.1-d,2-b,3-c,4-a        d.1-d,2-c,3-b,4-d	A
8. Which preparation is used in growth hormone deficiency (dwarfism) A.somatropin       b.somatrem    c.somatostatin      d.both a and b    e. All	D
9. Match following 1.octreotide          synthetic and used in acromegaly 2. Cabergoline      d2 agonist 3.nafareline           long acting gnrh agonist Select        A.      1-a,2-b,3-c               b. 1-b,2-a,3-c         C.1-c,2-b,3-a               d.1-a,2-c,3-b	A
10' Propylthiouracil inhibit peripheral conversion of t4 to t3 by inhibiting A.d1     b.d2     c.both      d.not inhibit peripheral conversion	A
11. Safe antithyroid therapy in pregnancy A.radioactive iodine     b.propylthiouracil C.carbimazol          d.all	B